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KMID : 0363220070450090942
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Korean Journal of Dermatology
2007 Volume.45 No. 9 p.942 ~ p.946
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Three Cases of Porokeratosis of Mibelli Treated with 5% Imiquimod Cream
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Yeon Je-Ho
Cho Kwang-Hyun
Park Hyun-Sun
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Abstract
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Porokeratosis is a disorder of epidermal keratinization that is histologically characterized by the presence of cornoid lamella. Many treatment modalities have been used, such as, surgical excision, cryosurgery, CO2 laser, oral etretinate, topical 5-fluorouracil and keratolytics. However, universal treatment guidelines have never been established. We tried 5% imiquimod cream on three patients who have porokeratosis of Mibelli which are intractable to other previous treatment modalities. Two of them showed a marked and moderate improvement, respectively. But the third patient exhibited only slight response. Herein we report our treatment experience and review the related literature.
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KEYWORD
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Imiquimod, Porokeratosis of Mibelli
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